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Published on: June 23, 2015
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Reporting ADPK Disease Phenotypes on Abdominal Scans.
Zhongxiu Hu1, Elizabeth G Lane1, Grace C Lo1
1Department of Radiology, Weill Cornell Medicine, New York, New York, USA.
Kidney International Reports
|September 22, 2025
Summary
Radiology reports for autosomal dominant polycystic kidney disease (ADPKD) often omit kidney and liver volumes, crucial biomarkers. Including these volumes and other key findings in reports will improve clinical utility for ADPKD management.
Area of Science:
- Radiology and Medical Imaging
- Nephrology and Urology
- Genetics and Genomics
Background:
- Kidney and liver volumes are vital biomarkers for monitoring autosomal dominant polycystic kidney disease (ADPKD) progression and treatment response, as per KDIGO guidelines.
- Accurate reporting of these biomarkers in radiological assessments is essential for effective patient management.
Purpose of the Study:
- To evaluate the frequency of reporting kidney and liver volumes in radiology reports for ADPKD.
- To assess the reproducibility of kidney volume measurements by radiologists.
Main Methods:
- Retrospective review of 145 abdominal MRI and CT studies by two independent observers.
- Discrepancy resolution by two senior radiologists and assessment of interobserver reproducibility for kidney volume measurements.
Main Results:
- Kidney volumes were reported in only 21% of outside reports, and liver volume in only 1% of relevant examinations.
- Kidney volume measurements showed a median absolute difference of 15% (ellipsoidal method) and 8% (model-assisted contouring) between outside and study radiologists.
- Other ADPKD-relevant findings like IVC compression were frequently underreported.
Conclusions:
- Current radiology reports for ADPKD often lack essential biomarkers like kidney and liver volumes.
- Improving the inclusion of recommended imaging features in reports can enhance their clinical utility for ADPKD management.
