Related Experiment Video
Updated: Jan 17, 2026

09:08
Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications
Published on: August 30, 2018
13.0K
Design and Development of a Simple Screw Mechanism for a Low-Cost Neonatal Syringe Pump
1Department of Biomedical and Imaging Sciences, King's College London, London, UK.
Medical Devices (Auckland, N.Z.)
|September 22, 2025
Summary
A new, low-cost open-source screw mechanism for syringe pumps was developed. This design offers high accuracy and fewer parts, potentially improving neonatal care in low-resource settings.
Area of Science:
- Biomedical Engineering
- Medical Device Design
- Neonatal Care Technology
Background:
- Neonatal mortality remains a significant global health challenge, with millions of deaths annually.
- Specialist neonatal care, including precise drug delivery via syringe pumps, is crucial for reducing infant mortality.
- Existing low-cost, open-source syringe pump designs have limitations, especially in resource-constrained environments.
Purpose of the Study:
- To design and evaluate a simple, open-source screw mechanism for potential integration into a low-cost syringe pump.
- To address the need for affordable and reliable neonatal care equipment in low-resource settings.
Main Methods:
- A prototype low-cost screw mechanism utilizing a non-captive stepper motor was engineered.
- Accuracy testing involved infusing saline using various syringe sizes (5mL, 20mL, 30mL, 60mL) at different rates.
- Flow rate error was calculated based on the time to infuse 75% of the nominal volume, adhering to ISO 286020:2020 standards.
Main Results:
- The prototype achieved a low total mean flow rate error of 0.38%±1.62%, well within the UNICEF/NEST360 target of 3%.
- The design features fewer components compared to other open-source alternatives.
- The mechanism demonstrated adaptability to a range of syringe sizes and superior accuracy compared to many existing designs.
Conclusions:
- The developed open-source screw mechanism shows promise for creating accurate, low-cost syringe pumps for neonatal care.
- This innovation could significantly enhance the quality of care in low-resource healthcare settings.
- Further research is recommended to test with diverse fluids, rates, and optimize software/hardware for enhanced accuracy.

