Dietary Fibre Intake in Older Adults Is Inversely Associated With Serum Remnant Cholesterol Level: A Nationwide...

Many studies have shown that dietary fibre lowers cholesterol levels; however, to our knowledge, no study has examined the relationship between dietary fibre intake and remnant cholesterol, which are known risk factors for cardiovascular disease (CVD). Therefore, we aimed to investigate the association between dietary fibre intake and remnant serum cholesterol levels in older Korean adults. We used data from the 2016 to 2021 Korea National Health and Nutrition Examination Survey, which included 8212 older adults. Serum remnant cholesterol levels were calculated by subtracting the low-density lipoprotein cholesterol and high-density lipoprotein cholesterol levels from the total cholesterol level. Hyperremnant cholesterolaemia was defined as a serum remnant cholesterol level of ≥ 30 mg/dL. Dietary fibre intake was classified on the basis of adequate intake (AI). A multivariate logistic regression analysis was performed to examine the association between dietary fibre intake and remnant serum cholesterol levels. The odds ratio of hyper-remnant cholesterol aemia was 1.26 times higher in older adults with fibre intake below AI than in those with fibre intake above AI (95% confidence interval 1.06-1.48, p < 0.01). This study revealed that dietary fibre intake was inversely associated with serum remnant cholesterol levels in older Korean adults. Therefore, dietary fibre can be considered a novel therapeutic strategy for lowering remnant cholesterol and may benefit older adults at risk of CVD in terms of the prevention and inhibition of progression.