Comparison of EfficientNet CNN models for multi-label chest X-ray disease diagnosis
Murat Ucan1, Buket Kaya2, Osman Aygun3
1Computer Technologies, Dicle (Tirgris) University, Diyarbakir, Turkey.
Peerj. Computer Science
|September 24, 2025
Summary
This study introduces a fast, lightweight deep learning model for autonomous chest X-ray disease detection. The novel architecture achieved high accuracy, aiding radiologists and improving diagnostic outcomes.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Computer Science
Background:
- Chest X-ray analysis is crucial but challenging due to complexity and potential for human error.
- Existing deep learning models for chest X-ray diagnosis often have high computational costs and limited success rates.
Purpose of the Study:
- To develop a novel, lightweight, and fast deep learning architecture for multi-class autonomous detection of 14 diseases from chest X-ray images.
- To improve upon the performance and reduce the computational cost of previous chest X-ray diagnostic models.
Main Methods:
- Utilized the ChestX-Ray14 dataset (112,104 labeled images) for training and testing.
- Implemented and evaluated eight EfficientNet architectures (B0-B7) integrated with a coordinate attention mechanism.
- Proposed a hybrid, attention-based deep learning architecture.
Main Results:
- The EfficientNetB7 model achieved an AUC of 0.8265.
- The EfficientNet enhanced with coordinate attention achieved a higher AUC of 0.8309.
- The proposed model demonstrated superior performance compared to existing studies, particularly for eight of the 14 disease classes.
Conclusions:
- The developed lightweight and fast deep learning architecture effectively supports radiologists in disease diagnosis.
- Autonomous diagnostic systems utilizing this technology can enhance healthcare by preventing misdiagnoses and underdiagnoses.
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