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The Role of Urinary Bladder Matrix in Preserving Length and Function After Fingertip Injury.
Meghan C McCullough1, Peggy J Ebner2, Theodore Brown1
1From the Department of Orthopaedic Surgery, Cedars Sinai Medical Center, Los Angeles, CA.
Plastic and Reconstructive Surgery. Global Open
|September 24, 2025
Summary
Urinary bladder matrix (UBM) aids fingertip injury reconstruction by promoting tissue regeneration and preserving length. This regenerative approach reduces the need for painful dressing changes and offers a viable alternative for complex hand injuries.
Area of Science:
- Regenerative Medicine
- Orthopedic Surgery
- Wound Healing
Background:
- Fingertip injuries are common and can lead to significant functional impairment.
- Reconstruction aims to preserve functional length and restore sensate, supple tissue.
- Urinary bladder matrix (UBM) shows potential as a tissue regenerator for these injuries.
Purpose of the Study:
- To evaluate the efficacy of Urinary Bladder Matrix (UBM) in reconstructing fingertip injuries.
- To assess outcomes such as wound healing time, need for skin grafting, and complications.
Main Methods:
- Retrospective review of 23 patients treated with UBM for hand/finger injuries (2020-2024).
- Data collected included demographics, injury type, and surgical outcomes.
- All patients underwent debridement followed by UBM application.
Main Results:
- UBM was used for various injuries including amputation/crush, burns, and ischemic necrosis.
- Average healing time was 9.8 weeks; 6 of 23 patients required secondary skin grafting.
- UBM was successfully used in 3 cases with preexisting infection.
Conclusions:
- Urinary bladder matrix (UBM) is a viable option for fingertip injury reconstruction.
- UBM facilitates soft tissue envelope regeneration and length preservation.
- It offers an alternative to secondary intention healing for complex fingertip defects.
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