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Intraoperative optical coherence tomography in ophthalmology: Technologies and applications
1Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Taiwan Journal of Ophthalmology
|September 25, 2025
Summary
Intraoperative optical coherence tomography (iOCT) enhances ophthalmic surgery by providing real-time visualization. This technology improves precision, surgical decision-making, and patient outcomes across various eye procedures.
Area of Science:
- Ophthalmology
- Medical Imaging
- Surgical Technology
Background:
- Intraoperative optical coherence tomography (iOCT) provides real-time, depth-resolved visualization during ophthalmic surgery.
- Early iOCT systems disrupted workflow; microscope-integrated systems now allow concurrent imaging.
- Advancements include faster imaging for 4D visualization and instrument tracking.
Purpose of the Study:
- To review the evolution and clinical utility of intraoperative optical coherence tomography (iOCT) in ophthalmic surgery.
- To highlight how iOCT augments decision-making, surgical precision, and the development of new techniques.
- To discuss the impact of iOCT on surgical performance and patient outcomes.
Main Methods:
- Review of technological advancements in iOCT systems for ophthalmic applications.
- Analysis of iOCT integration into surgical microscopes and visualization methods.
- Summary of clinical applications and demonstrated utility in various ophthalmic procedures.
Main Results:
- Microscope-integrated iOCT systems overcome workflow limitations of earlier devices.
- Heads-up displays enhance iOCT visualization ergonomics and surgeon focus.
- iOCT has shown utility in diverse procedures like glaucoma surgery, cataract extraction, and retinal repair.
Conclusions:
- iOCT significantly enhances ophthalmic surgical capabilities through real-time visualization.
- Technological integration, including speed and tracking, is crucial for iOCT's advancement.
- iOCT holds substantial potential to improve surgical performance and patient outcomes in ophthalmology.

