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Related Experiment Video

Updated: Jan 17, 2026

Functional Assessment of Intestinal Permeability and Neutrophil Transepithelial Migration in Mice using a Standardized Intestinal Loop Model
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Active-Supervised Model for Intestinal Ulcers Segmentation Using Fuzzy Labeling.

Jie Chen, Yanning Lin, Faisal Saeed

    IEEE Journal of Biomedical and Health Informatics
    |September 25, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Machine learning improves inflammatory bowel disease (IBD) diagnosis by enhancing intestinal ulcer segmentation. Novel algorithms address noisy labels and dataset variations for more accurate and efficient IBD detection.

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    Area of Science:

    • Medical imaging analysis
    • Artificial intelligence in gastroenterology
    • Computational pathology

    Background:

    • Inflammatory bowel disease (IBD) diagnosis relies on colonoscopy, but current image analysis is subjective and inefficient.
    • Accurate intestinal ulcer segmentation is crucial for IBD diagnosis but faces challenges like noisy labels and dataset variability.
    • Existing methods struggle with the complexity and subjectivity of manual image scoring, impacting diagnostic accuracy.

    Purpose of the Study:

    • To develop advanced machine learning techniques for precise intestinal ulcer segmentation in IBD diagnosis.
    • To address the challenges of labeling noise and performance variability in medical image segmentation models.
    • To enhance the accuracy and efficiency of IBD diagnosis through multi-category ulcer segmentation.

    Main Methods:

    • Proposed an active ulcer segmentation algorithm utilizing fuzzy labeling and collaborative training.
    • Implemented a segmentation model that leverages pixel-wise confidence from fuzzy labels for robustness against noisy annotations.
    • Introduced a data adaptation strategy with active learning to select informative samples, improving model adaptability across diverse datasets.

    Main Results:

    • The collaborative training model demonstrated enhanced robustness to noisy labels through network cooperation.
    • The active learning strategy significantly improved model performance and adaptability across different public and hospital datasets.
    • Experimental validation confirmed the effectiveness of the proposed methods in handling segmentation challenges.

    Conclusions:

    • The developed machine learning approach offers a more precise and efficient method for IBD diagnosis.
    • Addressing noisy labels and dataset variability is key to improving automated medical image analysis for IBD.
    • This research paves the way for improved diagnostic tools in gastroenterology, aiding in early and accurate IBD detection.