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Author Spotlight: Mitochondrial Remodeling in Skeletal Muscle
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Mitochondrial cardiolipin remodeling facilitates efficient myoblast differentiation

Yohsuke Ohba1, Chinami Fujiwara2, Makoto Arita3

  • 1Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan; Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa, Japan.

Journal of Lipid Research
|September 25, 2025
PubMed
Summary

Mitochondrial cardiolipin remodeling, specifically increasing linoleic acid content, is crucial for efficient myoblast differentiation. This process is essential for muscle cell development and function.

Keywords:
cell signalinglipidomicsmitochondriamusclephospholipid

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