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Updated: Jan 16, 2026

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
[Respirator in New Technology for Respiratory Medicine]
1Department of Thoracic Surgery, Fujita Health University, Toyoake, Japan.
Abstract:
According to the progress in medical devices, respirators are improving to avoid ventilator-associated lung injury with new technology and concepts. At first, we need to know the methods of respirator settings; they are the respiratory mode and method. Respiratory modes are assist/control (A/C), synchronized intermittent mandatory ventilation (SIMV), and continuous positive airway pressure (CPAP). The respiratory methods are volume-controlled ventilation (VCV), pressure-controlled ventilation (PCV), and pressure support ventilation (PSV). The new methods of ventilation are airway pressure release ventilation (APRV) and neurally adjusted ventilatory assist (NAVA). To protect the lung injury by ventilation, we need to control the limitation of ventilation volume in one breath, high positive end-expiratory pressure, plateau pressure in lung alveoli, auto positive end-expiratory pressure, and driving pressure in respiration. Coming to the new devices, lung injury would be mitigated by mechanical ventilation.
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