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Updated: Jan 16, 2026

Characterizing Lewis Pairs Using Titration Coupled with In Situ Infrared Spectroscopy
Published on: February 20, 2020
A reflection on frustrated Lewis pairs 20 years on: the gift that keeps on giving
Rebecca L Melen1, Douglas W Stephan2
1Cardiff Catalysis Institute, School of Chemistry, Cardiff University, Translational Research Hub Maindy Road, Cathays Cardiff Cymru/Wales CF24 4HQ UK MelenR@cardiff.ac.uk.
None:
This commentary reflects on the remarkably broad impact the concept of "frustrated Lewis pairs" (FLPs) has had over the past 20 years. Since its initial articulation, this concept has found applications across the periodic table and the discipline, leading to new avenues for synthesis and catalysis, building on the 2011 publication (R. C. Neu, E. Otten, A. Lough and D. W. Stephan, Chem. Sci., 2011, 2, 170, https://doi.org/10.1039/C0SC00398K).
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