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Updated: Jun 27, 2026

High-resolution Thermal Micro-imaging Using Europium Chelate Luminescent Coatings

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Published on: April 16, 2017

Multifunctional Fluorescent Microgel-Embedded Hydrogels for Temperature and X-Ray Sensing.

Hao Jiang¹, Luyao Wang², Li Jiang³

¹Key Laboratory of Polymeric Material Design and Synthesis for Biomedical Function, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou, 215123, China.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

|September 30, 2025

Summary

This summary is machine-generated.

This study developed dual-responsive hydrogels using aggregation-induced emission luminogens (AIEgens) for sensing skin temperature and X-ray dosage. These smart hydrogels offer accurate diagnostics and radiotherapy monitoring.

Keywords:

aggregation‐induced emission luminogen ratiometric fluorescent sensing stimuli‐responsive hydrogel support vector machine regression

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Area of Science:

Materials Science
Biomedical Engineering
Chemical Engineering

Background:

Stimuli-responsive hydrogels offer tunable fluorescent signals for sensing applications.
Monitoring skin temperature and X-ray dosage is vital for disease diagnosis and cancer radiotherapy.

Purpose of the Study:

To develop dual-responsive hydrogels for sensing skin temperature and X-ray dosage.
To investigate the enhancement of mechanical and adhesive properties of polyvinyl alcohol (PVA) hydrogels.

Main Methods:

Incorporation of ratiometric fluorescent aggregation-induced emission luminogen (AIEgen)-based microgels into PVA.
Experimental characterization and molecular dynamics (MD) simulations.
Support vector machine (SVM) regression for spectral accuracy.

Main Results:

AIEgen microgels improved PVA hydrogel mechanical strength and adhesion while maintaining biocompatibility.
Dual-responsive hydrogels exhibited spectral and visual fluorescent signal variations with temperature and X-ray exposure.
SVM regression enabled accurate spectral analysis for sensing applications.

Conclusions:

The developed hydrogels accurately sense skin temperature and map radiotherapy dose levels.
This technology provides a promising platform for real-time physiological monitoring and radiation dosimetry.