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Updated: Jan 16, 2026
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Published on: September 5, 2017
Fibrous Dysplasia of Frontal Process of Maxilla: False-Positive Finding on 18F-FDG PET in Multiple Myeloma
Fathima Fijula Palot Manzil1, Pokhraj Suthar2, Surjith Vattoth2
1Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, Illinois drfijulasurjith@yahoo.com.
Abstract:
18F-FDG focal uptake in bone is always concerning, especially in patients with a history of cancer. We report a case of increasing hypermetabolic activity of a maxillary bone lesion in a patient with a history of multiple myeloma that was managed with definitive treatment. A targeted CT scan revealed that the abnormal 18F-FDG uptake was fibrous dysplasia. Vigilant interpretation is required for focal osseous activity on PET/CT in patients with a history of cancer to avoid false-positive readings.
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