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Early Outcomes Using TIGR Mesh in Direct-to-Implant Breast Reconstruction.

Orr Shauly1, Makenna Ash2, Shannon Su2

  • 1From the Division of Plastics and Reconstructive Surgery, Emory University, Atlanta, GA.

Plastic and Reconstructive Surgery. Global Open
|October 3, 2025
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Summary
This summary is machine-generated.

TIGR Matrix shows promising early outcomes in direct-to-implant breast reconstruction, offering a potentially cost-effective synthetic mesh option. Further research is needed for long-term effectiveness.

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Area of Science:

  • Plastic Surgery
  • Biomaterials Science
  • Oncology

Background:

  • Direct-to-implant (DTI) breast reconstruction often utilizes soft tissue support to enhance outcomes and minimize implant displacement.
  • Synthetic meshes, like TIGR Matrix, are being explored as alternatives to biological materials due to potential cost savings and reduced complication rates.

Purpose of the Study:

  • To evaluate the early outcomes of using TIGR Matrix as a synthetic mesh in immediate direct-to-implant breast reconstruction.
  • To assess the safety and efficacy profile of TIGR Matrix in this specific reconstructive setting.

Main Methods:

  • A retrospective chart review of patients undergoing DTI breast reconstruction with TIGR Matrix between November 2023 and June 2024.
  • Inclusion criteria required DTI reconstruction and a minimum of 6 months follow-up.
  • Data on patient demographics, oncological and reconstructive details, comorbidities, and postoperative complications were collected and analyzed.

Main Results:

  • The study included 71 patients (109 breasts), with various mastectomy types (nipple-sparing, skin-sparing, Goldilocks).
  • The overall major complication rate was 12.8%, including hematomas, seromas, infections, and explantations. Reoperation was required in 10.1% of patients.
  • Minor complications, such as delayed wound healing, were observed in 17.4% of breasts.

Conclusions:

  • TIGR Matrix presents an acceptable early complication profile for direct-to-implant breast reconstruction.
  • It may serve as a viable, cost-effective alternative to acellular dermal matrices.
  • Long-term outcome assessment and comparative effectiveness studies are warranted.