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Updated: Jan 15, 2026

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
[Emerging Multimodality Imaging Techniques for the Pulmonary Circulation]
Elena Pfeuffer-Jovic1, Kai Helge Schmidt2,3, Teresa John4
1Medizinische Klinik mit Schwerpunkt Pneumologie und Beatmungsmedizin, Klinikum Würzburg Mitte gGmbH, Würzburg, Deutschland.
Abstract:
Pulmonary hypertension (PH) is a complex and heterogeneous disease, which complicates its precise classification, diagnosis, and treatment. Established approaches for assessing PH include echocardiography, lung scintigraphy, and cross-sectional imaging using CT and MRI, which, however, only indirectly reveal the underlying pathology. Novel imaging techniques currently exist that allow for comprehensive assessment of lung perfusion and cardiopulmonary interaction. This article summarizes the current state of research regarding novel multimodal imaging techniques and the simultaneous application of AI in the field of PH. These novel methods promise to improve our understanding of the pathomechanisms of this diagnostically challenging disease. This could make diagnosis and classification more precise and complement treatment planning and patient monitoring. However, further steps are necessary for widespread application, and also equipment and personnel availability are limiting.
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