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Updated: Jan 15, 2026

Expression, Purification, Crystallization, and Enzyme Assays of Fumarylacetoacetate Hydrolase Domain-Containing Proteins
Published on: June 20, 2019
Fungal α-carbonic anhydrases
Katia D'Ambrosio1, Anna Di Fiore1, Vincenzo Alterio1
1Institute of Biostructures and Bioimaging - CNR, Napoli, Italy.
None:
Carbonic anhydrases (CAs) are widely distributed in the fungal kingdom and play crucial roles for their growth, development, virulence, and survival. Known fungal CAs belong either to the α- or the β-classes, with the α-class encoded only in filamentous ascomycetes. Here we report the main findings relative to α-CAs characterized so far from different fungi, namely Aspergillus oryzae, Sordaria macrospora and Paracoccidioides. Structural, functional and biochemical data will be discussed underlying the necessity of more research efforts to gain a comprehensive understanding of fungal α-CAs.
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