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Tuning the Acidity of Pt/ CNTs Catalysts for Hydrodeoxygenation of Diphenyl Ether
Published on: August 17, 2019
Cu-catalyzed oxygen-transferring hydrazonation of enynones
Shaotong Qiu1, Yangxin Mao1, Zhicheng Yang1
1Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China. qiust@hnust.edu.cn.
Abstract:
An unprecedented Cu-catalyzed oxygen-transferring hydrazonation reaction of enynones with arylsulfonylhydrazines has been developed. Featuring high efficiency, broad substrate scope and mild reaction conditions, this protocol provides a practical alcohol-free approach to access various bio-related aryl-alkenyl and aryl-aryl sulfonylhydrazones containing carbonyl groups in up to 97% yields, which are challenging to synthesize via conventional methods. The utility of this reaction is further demonstrated by transformation of the obtained molecules into diverse nitrogen-containing heterocyclic compounds and alkenyl or hydroxyl derivatives.
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