[Translated article] Home Self-Applied Daylight Photodynamic Therapy: Current Map in Spain and Management Proposals
T Gracia-Cazaña1, Y Gilaberte1
1Servicio de Dermatología, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain.
Actas Dermo-Sifiliograficas
|October 11, 2025
Summary
Spanish dermatologists use home self-applied daylight photodynamic therapy (dPDT) effectively for AK treatment. Patient satisfaction is high, but protocolizing dPDT is recommended for improved safety and efficacy.
Area of Science:
- Dermatology
- Photodynamic Therapy
- Oncology
Background:
- Daylight photodynamic therapy (dPDT) is an effective treatment for actinic keratosis (AK).
- Home self-application of dPDT offers a convenient alternative to in-clinic treatments.
- Understanding current practices is crucial for optimizing dPDT protocols.
Purpose of the Study:
- To assess the current practices and experiences of Spanish dermatologists with self-applied dPDT.
- To identify trends in dPDT application, patient selection, and satisfaction.
Main Methods:
- A retrospective, multicenter, cross-sectional observational study.
- 100 Spanish dermatologists participated via an online questionnaire.
- Data collected included experience, climatology, advantages, disadvantages, and satisfaction.
Main Results:
- 38.4% of dermatologists have over 5 years of dPDT experience; 72.7% alternate clinic and home application.
- 61.1% lack specific self-application protocols, though 69.4% provide personal instructions.
- 50% prefer applying dPDT during months with higher solar activity, and 70.8% recommend morning treatments.
Conclusions:
- Self-applied dPDT is an effective, well-tolerated treatment for AK, particularly with patient adherence and family support.
- Protocolizing self-applied dPDT is necessary to enhance safety and efficacy in home settings.
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