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Updated: Jan 6, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Out of breath at night-obstructive sleep apnoea is the most prevalent physical sleep disorder]
Holger Woehrle1, Verena Kümmerlen2, Katja Thiess2
1Schlaf- und Beatmungszentrum Blaubeuren, Lungenzentrum Ulm, Olgastr. 83, 89073, Ulm, Deutschland. hwoehrle@lungenzentrum-ulm.de.
Abstract:
Obstructive sleep apnea (OSA) is one of the most common widespread diseases and is associated with significant health risks and a considerable reduction in quality of life. Treatment is multimodal. Risk assessment tools such as the STOP-BANG questionnaire are commonly used, while the Epworth Sleepiness Scale helps evaluate subjective daytime sleepiness. Sleep studies play a central role in diagnosis. While in-lab polysomnography is considered the gold standard, for many patients, home sleep apnea testing (HSAT) using polygraphy provides sufficient objective data to confirm the diagnosis. The primary treatment option is positive airway pressure (PAP) therapy. In addition, alternative approaches are available today, including mandibular advancement devices (MAD), hypoglossal nerve stimulation, and positional therapy. Long-term treatment success depends on good therapy adherence and structured follow-up care - for example, using the S-O-S scheme.
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