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The Usefulness of Inclusion of Visual Field Tests Using Multiple Testing Strategies in Perimetric Rate of Progression
Yusuke Noda1, Ryo Asaoka1,2,3,4, Kazunori Hirasawa5
1Department of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan.
Translational Vision Science & Technology
|October 14, 2025
Summary
Including prior Swedish Interactive Thresholding Algorithm (SITA) Fast visual field data improves mean total deviation (mTD) trend analysis accuracy in glaucoma patients. This combination enhances predictions for future visual field progression.
Area of Science:
- Ophthalmology
- Visual Electrophysiology
- Glaucoma Research
Background:
- Glaucoma management relies on accurate visual field (VF) trend analysis.
- Mean total deviation (mTD) is a key metric for assessing glaucoma progression.
- Swedish Interactive Thresholding Algorithm (SITA) Fast and Standard are common VF testing strategies.
Purpose of the Study:
- To validate the combined use of SITA Fast and SITA Standard algorithms for mTD trend analysis.
- To assess the impact of incorporating SITA Fast data on the accuracy of mTD predictions.
Main Methods:
- Retrospective analysis of 128 eyes from 95 open-angle glaucoma patients.
- Compared prediction errors of future VFs using varying numbers of SITA Standard VFs alone versus combined with SITA Fast VFs.
- Iterative calculations were performed with and without adjusting for differences between SITA Fast and Standard VFs.
Main Results:
- Prediction errors significantly decreased from 10.40 dB (2 SITA Standard VFs) to 2.83 dB when SITA Fast VFs were included.
- Adjusting for the difference between SITA Fast and Standard VFs did not significantly alter prediction error.
- With 4 SITA Standard VFs, prediction errors ranged from 2.12 to 2.34 dB, with no significant differences between methods.
Conclusions:
- Incorporating prior SITA Fast VF data enhances the accuracy of mTD trend analysis using SITA Standard VFs.
- Clinically, combining both SITA Fast and Standard VFs is beneficial for mTD trend analysis in glaucoma patients.
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