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Updated: Jan 15, 2026

Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
[Research progress on olfactory function and rehabilitation after total laryngectomy]
Xingqi Zhu1, Xiaoyun Qian1, Yajun Gu1
1Department of Otorhinolaryngology Head and Neck Surgery,Affiliated Drum Tower Hospital,Medical School of Nanjing University,Nanjing,225411,China.
Abstract:
Total laryngectomy is a crucial surgical intervention for patients with advanced malignant tumors of the larynx and nasopharynx. Despite its effectiveness, this procedure permanently severs the connection between the nasal cavity and the lower respiratory tract, leading to the cessation of nasal airflow. This disruption significantly impairs the patient's sense of smell and adversely affects their quality of life. Although olfactory loss is common in these patients, the assessment and rehabilitation of their olfactory function are often overlooked. This article reviews relevant literature on evaluating olfactory function and rehabilitation methods following total laryngectomy, with the aim of providing a theoretical foundation to enhance olfactory rehabilitation and overall quality of life for these patients.
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