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[Symptomatic Narcolepsy due to Neurological Disorders]
Keisuke Suzuki1, Hiroaki Fujita, Ryoma Takahashi
1Department of Neurology, Dokkyo Medical University.
Abstract:
Narcolepsy is a major central disorder of hypersomnolence that causes excessive daytime sleepiness (EDS), cataplexy, sleep paralysis and hypnagogic hallucinations due to impairment of the orexinergic system. Symptomatic narcolepsy is characterized by persistent EDS and REM sleep-related symptoms due to associated neurological diseases or brain lesions. Hypothalamic lesions due to neurological disorders, including immune-mediated diseases, can cause symptomatic narcolepsy. This review describes symptomatic narcolepsy and EDS associated with neurological disorders.
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