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Slipped Capital Femoral Epiphysis in a Case of Hyperphosphatemic Familial Tumoral Calcinosis: A Case Report
Sreekanth Kashayi-Chowdojirao1, Safia Sultana1, Prajnya Ranganath2
1Department of Orthopaedics, Nizam's Institute of Medical Sciences, Hyderabad, India.
Case:
An Indian girl, diagnosed with osteoid osteoma of tibia and chronic recurrent multifocal osteomyelitis at the age of 6 years, presented 3 years later with slipped capital femoral epiphysis (SCFE) and was found to have a mutation in the GALNT3 gene associated with hyperphosphatemic familial tumoral calcinosis. She underwent in situ screw fixation with prophylactic pinning of the other hip. At a 2-year follow-up, the patient had a good range of motion and no radiological signs of osteonecrosis of the femoral head.
Conclusion:
GALNT3 gene mutation with SCFE is a previously unreported association, emphasizing the need for a multidisciplinary approach.
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