Immediate Bilateral Sequential Keratoplasty in a 13-Year-Old Boy With Perforated Corneal Ulcer Secondary to Exposure

Javad Sadeghi1, Mohammadreza Sedaghat1, Mitra Karimi Amir Abadi1

  • 1Eye Research Center Mashhad University of Medical Sciences Mashhad Iran.

Clinical Case Reports
|October 17, 2025
PubMed

Insights

Immediate sequential bilateral penetrating keratoplasty (PKP) successfully treated a pediatric patient with bilateral corneal perforations. This approach offers a viable solution for emergent cases, preventing further vision loss and complications.

Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Bilateral corneal perforations present a critical ophthalmic emergency.
  • Prompt intervention is crucial to prevent vision loss and endophthalmitis.

Purpose of the Study:

  • To report the first case of immediate sequential bilateral penetrating keratoplasty (PKP).
  • To evaluate the treatment outcomes of this emergent surgical approach in a pediatric patient.

Main Methods:

  • A 13-year-old patient with bilateral corneal perforations underwent immediate sequential bilateral PKP.
  • The surgical procedure involved sequential corneal transplantation in both eyes.

Main Results:

  • The patient experienced successful outcomes with no graft rejection or infection at 6-month follow-up.
  • Immediate sequential bilateral PKP was effective in managing the critical condition.

Conclusions:

  • Immediate sequential bilateral PKP is a safe and effective treatment for bilateral corneal perforations.
  • This surgical strategy is a reasonable option in emergent ophthalmic scenarios.