Clinical Presentation of the Celiac Disease Patient

Celiac disease (CeD) presents with a wide array of symptoms, affecting nearly every organ system. This review describes CeD clinical presentation at diagnosis, covering both gastrointestinal and extraintestinal manifestations. Notably, although some individuals exhibit symptoms, family and population studies show that a substantial number of cases go undetected due to the absence of typical signs, leading to overlooked diagnoses. This review also aims to heighten awareness of CeD presentation among not only gastroenterologists and pediatricians but also specialists across various medical fields, who together play a crucial role in early detection and prevention of irreversible harm.