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Updated: Jan 6, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Imidazo[1,5]carbachlorin as a hybrid ligand
Kinga Szydełko1, Sebastian Koniarz1, Michał J Białek1
1Department of Chemistry, University of Wrocław, F. Joliot-Curie 14, 50 383 Wrocław, Poland. piotr.chmielewski@uwr.edu.pl.
None:
A family of novel complexes of imidazo[1,5]carbachlorin has been synthesized and characterized by spectroscopic, X-ray diffraction, and electrochemical methods. In most of these compounds, both the macrocyclic crevice and the fused external imidazole are involved in the coordination of the metal ion, thus defining imidazocarbachlorin as a hybrid ligand system consisting of NNNC- and N-donor sets. The effect of the external coordination on the shape of the macrocyclic ring has been studied and discussed.
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