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Updated: May 5, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
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Visualizing the Global Landscape of Post-transplant Acute Lung Rejection
Niki R Patel1, Meghana Konda2, Latha Ganti3
1Biology, Canterbury Collegiate Preparatory High School, Fort Myers, USA.
Antibody-mediated rejection poses a significant threat after lung transplantation, despite advancements in antibody matching. This bibliometric analysis reviews research trends from 2016-2025 to identify patterns in lung transplant rejection.
Area of Science:
- Immunology
- Transplantation Medicine
- Bibliometrics
Background:
- Antibodies can rapidly attack donor lungs post-transplantation, leading to antibody-mediated rejection.
- Challenges persist in detecting and treating lung transplant rejection, exacerbated by the lung's environmental exposure.
- Persistent rejection and aggressive treatments negatively impact patient survival rates.
Purpose of the Study:
- To conduct a bibliometric analysis of research on lung transplantation and rejection.
- To identify emerging patterns and trends in the literature from 2016 to 2025.
- To analyze countries, institutions, publication years, and keywords related to acute lung transplant rejection.
Main Methods:
- Bibliometric analysis of research publications.
- Citation analysis from the Web of Science database.
- Trend analysis using VOSviewer software.
Main Results:
- Identification of key research contributors (countries, institutions).
- Mapping of publication trends over time (2016-2025).
- Analysis of prevalent keywords and research themes in lung transplant rejection.
Conclusions:
- The study provides a comprehensive overview of the research landscape in lung transplantation and rejection.
- Insights into global research activity and collaboration patterns are highlighted.
- Emerging trends and focus areas in addressing lung transplant rejection are identified.
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