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Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
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Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
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The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
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Related Experiment Video

Updated: Jan 14, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
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[Functional neurological disorders].

Béatrice Garcin1

  • 1Service de neurologie, hôpital Avicenne, Bobigny, France.

La Revue Du Praticien
|October 23, 2025
PubMed
Summary

Functional Neurological Disorders (FND) involve brain network dysfunctions causing various symptoms. Effective management requires clear diagnosis, multidisciplinary care, and addressing risk factors for reduced patient vulnerability.

Area of Science:

  • Neurology
  • Neuroscience
  • Psychiatry

Background:

  • Functional Neurological Disorders (FND) are neurological conditions involving brain network dysfunctions.
  • Symptoms include motor deficits, functional dissociative seizures, speech disorders, and sensory deficits.
  • FND affects 15% of neurology consultations, with a prevalence of 0.5-1/1000.

Purpose of the Study:

  • To summarize the key aspects of Functional Neurological Disorders.
  • To outline diagnostic criteria and management strategies for FND.

Main Methods:

  • Diagnosis relies on DSM-5-TR criteria, emphasizing positive clinical signs.
  • Neuroimaging studies reveal associated brain dysfunctions.
  • Assessment involves identifying predisposing, precipitating, and perpetuating risk factors.
Keywords:
Nervous System Diseases

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Functional Near Infrared Spectroscopy of the Sensory and Motor Brain Regions with Simultaneous Kinematic and EMG Monitoring During Motor Tasks
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Related Experiment Videos

Last Updated: Jan 14, 2026

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Event-related Potentials During Target-response Tasks to Study Cognitive Processes of Upper Limb Use in Children with Unilateral Cerebral Palsy
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Main Results:

  • FND symptoms are linked to brain network dysfunctions, often triggered by trauma in vulnerable individuals.
  • Imaging studies confirm brain network alterations in FND patients.
  • Effective treatment necessitates a clear diagnosis and a multidisciplinary approach.

Conclusions:

  • FND management requires a clear diagnostic explanation and a multidisciplinary approach, including physiotherapy and psychotherapy.
  • Identifying and treating risk factors is crucial for reducing patient vulnerability and improving outcomes.
  • Understanding FND as a brain network disorder is key to effective patient care.