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Updated: Feb 25, 2026
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Author Spotlight: Methodologies and Advancements of Chronic Pain Management Research
Published on: January 5, 2024
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Characterisation of Chronic Pain Syndrome in Patients With Functional Neurological Disorder
Sarah Azzopardi1,2, Béatrice Garcin3,4, Francine Mesrati2
1ENT Team, UR4391, Faculty of Health, Paris Est Créteil University, Créteil, France.
European Journal of Pain (London, England)
|February 24, 2026
Summary
Chronic pain is a frequent and impactful symptom in functional neurological disorders (FNDs), often linked to central sensitization mechanisms. Effective management strategies are crucial for improving patient quality of life.
Area of Science:
- Neurology
- Pain Medicine
- Psychiatry
Background:
- Functional neurological disorders (FNDs) present with neurological symptoms not explained by other conditions.
- Chronic pain frequently co-occurs with FND, though not a diagnostic criterion.
Purpose of the Study:
- To determine the frequency of chronic pain in FND patients.
- To characterize the mechanism-based features of chronic pain in FND.
Main Methods:
- Prospective data collection from a single-center cohort.
- Standardized questionnaires and face-to-face interviews were utilized.
Main Results:
- 86% of 63 FND patients reported chronic pain.
- Pain onset linked to trauma in 41%; 65% described it as permanent.
- Pain characteristics suggest neuropathic or central sensitization mechanisms over nociceptive origins.
Conclusions:
- Chronic pain is the most common symptom in FND, significantly impacting daily life.
- Pain in FND is heterogeneous, necessitating optimized symptomatic treatments and management strategies.
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