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Related Concept Videos

Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Updated: Jan 14, 2026

Author Spotlight: Advancing Hepatobiliary and Pancreatic Tumor Treatment with Minimally Invasive Surgical Techniques
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Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies.

Alejandro Chara1, Katlyn G McKay1, Harold N Lovvorn2

  • 1Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

European Journal of Haematology
|October 24, 2025
PubMed
Summary

Minimally invasive surgery (MIS) offers a safe approach for pediatric hematologic malignancy patients, aiding diagnosis and managing complications. Further research is needed to confirm its benefits and explore advanced techniques.

Keywords:
augmented realitylaparoscopyminimally invasive surgeryrobotic surgerythoracoscopy

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Area of Science:

  • Pediatric Oncology
  • Surgical Oncology
  • Minimally Invasive Surgery

Background:

  • Hematologic malignancies are the most common childhood cancers.
  • Treatment primarily involves chemotherapy and stem cell transplant.
  • Minimally invasive surgery (MIS) plays a role in managing complications and common surgical issues in these patients.

Purpose of the Study:

  • To evaluate the role and safety of MIS in pediatric patients with hematologic malignancies.
  • To explore MIS applications in diagnosing and managing disease-related complications and therapy adverse events.
  • To assess MIS utility in addressing common surgical conditions in this patient population.

Main Methods:

  • Review of current evidence on MIS utilization in pediatric hematologic malignancy patients.
  • Analysis of MIS applications including diagnosis (biopsy) and management of complications (e.g., perforation, pneumatosis).
  • Consideration of MIS for common surgical problems (e.g., enteral access, appendicitis, cholecystitis) to facilitate treatment continuity.

Main Results:

  • MIS is a safe and feasible approach for various surgical problems in pediatric patients with hematologic malignancies.
  • It can serve as a diagnostic tool (biopsy) and a management option for complications.
  • Laparoscopic approaches can enable a faster return to chemotherapy for common surgical issues.

Conclusions:

  • MIS is a valuable tool in the multidisciplinary care of pediatric patients with hematologic malignancies.
  • Current evidence is primarily based on retrospective data; prospective studies are needed.
  • Further research should validate MIS approaches and investigate emerging technologies like robotics and augmented reality.