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Understanding sex-related differences in peritoneal dialysis: Evidence, limitations, and next steps
Charat Thongprayoon1, Wisit Kaewput2, Wisit Cheungpasitporn1
1Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
None:
We appreciate Dr Akcay's insightful comments. His observations provide valuable context and highlight important considerations for future research. We hope our work will serve as a foundation for further investigation into sex-associated risks in peritoneal dialysis and contribute to optimizing high-quality patient care for all individuals. Looking ahead, future studies should integrate dialysis-specific measures, explore mechanistic pathways, and incorporate patient-centered outcomes to better characterize sex-associated differences in peritoneal dialysis.
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Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...

