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Early Predictors of Atopic Dermatitis and Food Allergy
Myongsoon Sung1, Byung Eui Kim2, Donald Y M Leung2
1Department of Pediatrics, National Jewish Health, Denver, CO 80206, USA; Department of Pediatrics, Soonchunhyang University Gumi Hospital, Gumi, Republic of Korea.
Immunology and Allergy Clinics of North America
|October 24, 2025
Summary
Early prediction of atopic dermatitis (AD) and food allergy (FA) in infants is crucial. Skin tape stripping offers a noninvasive method to identify biomarkers for early intervention and disease management.
Area of Science:
- Dermatology and Allergy Research
Background:
- Atopic dermatitis (AD) and food allergy (FA) affect many infants, with early intervention being key.
- Predicting AD and FA involves analyzing genetics, skin barrier, lipids, cytokines, microbiome, and environmental factors.
Purpose of the Study:
- To explore the pathogenesis of AD and FA.
- To highlight skin tape stripping as a noninvasive tool for identifying predictive biomarkers in infants.
Main Methods:
- Review of research on AD and FA pathogenesis.
- Analysis of factors including genetics, skin barrier function, and environmental influences.
- Exploration of skin tape stripping for biomarker identification.
Main Results:
- Significant interest exists in early AD and FA prediction using various factors.
- Skin tape stripping shows potential as a noninvasive tool for biomarker discovery.
Conclusions:
- Early identification of infants at risk for AD and FA is critical.
- Skin tape stripping is a promising noninvasive approach for identifying predictive and follow-up biomarkers.
Keywords:
Atopic dermatitisEnvironmentsFood allergyGeneticsImmune dysregulationPredictionSkin barrierSkin barrier dysfunctionMore Related Videos
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