Related Experiment Video
Updated: Jan 13, 2026

Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle VLP-Based Vaccines Using a Capture Assay
Published on: February 10, 2022
Virosomes: Beyond Vaccines
Hadeel K Salameh1, Mohammed M Safi1, Rafik Karaman1,2
1Pharmaceutical Sciences Department, Faculty of Pharmacy, Al-Quds University, Jerusalem 20002, Palestine.
None:
Background: One of the primary strategies for preventing and reducing infectious diseases is vaccination. There are numerous licensed vaccinations of various kinds that can prevent viral infection by triggering the immune system's reaction to specific antigens beforehand. To elicit a stronger immune response, however, two elements of the immune system-humoral and cellular immunity-should be addressed. Since they target proteins that are difficult to alter, recent innovative techniques for vaccine delivery systems-such as liposomes, nanogels, microemulsions, etc.-have shown excellent immunogenicity qualities. Methods: PubMed, ScienceDirect, and Google Scholar were used as the databases for literature search, and keywords such as "Virosomes", "Hemagglutinin", and "IRIV" were selected to ensure relevant articles were included. Results: This article examines a cutting-edge method called virosomes, which are an effective way to deliver pharmaceutically active ingredients that target a variety of illnesses and ailments, as well as vaccines. This resulted from the fact that virosomes possess numerous structural characteristics that might trigger sophisticated immune reactions by utilizing the inactivated virus's envelope or by imitating it through recombinant methods. Conclusions: Here, we will walk you through the history of virosome development, explore various manufacturing techniques, provide an overview of the latest patents, and conclude with the potential for more virosomal revolutions.
Related Concept Videos
Vaccinations
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
Microorganisms in Medicine and Therapeutics
Viral Mutations
Retroviruses
Retrovirus Life Cycles

