Insights into endometrial cancer management: a comprehensive guide through multimodality imaging

Area of Science:

• Gynecologic Oncology
• Radiology
• Medical Imaging

Background:

• Endometrial cancer is a common gynecologic malignancy with variable prognosis and treatment.
• Multimodality imaging plays a vital role throughout the patient care pathway.
• Accurate staging and risk stratification are essential for effective management.

Purpose of the Study:

• To review the critical role of multimodality imaging in endometrial cancer management.
• To highlight how imaging influences diagnosis, staging, surgical planning, and treatment selection.
• To discuss the impact of advanced imaging techniques on personalized care.

Main Methods:

• Review of current literature on multimodality imaging in endometrial cancer.
• Inclusion of ultrasound, MRI, CT, and PET/CT in the analysis.
• Emphasis on functional and quantitative imaging techniques like DWI.

Main Results:

• Imaging is essential for tumor characterization, staging (local/distant), and detecting nodal/peritoneal disease.
• Imaging guides surgical decisions (conservative vs. radical), sentinel lymph node mapping, and adjuvant therapies.
• Advanced imaging, including DWI, enhances disease grading and treatment tailoring.

Conclusions:

• Standardized management algorithms and multiparametric imaging assessments are necessary for optimal risk stratification.
• Imaging biomarkers hold evolving potential for personalizing endometrial cancer management.
• Integrating advanced imaging techniques can improve patient outcomes in endometrial cancer care.