Elysee Exosome Versus Cellbooster Lift in Oral Wound Healing

The objective of this study was to evaluate the efficacy of injecting Elysee exosomes or Cellbooster Lift in promoting the healing of oral mucosal wounds.

Thirty-six adult Wistar Albino rats were randomly divided into 3 groups. Group 1 served as the control group and underwent a scalpel incision in the oral mucosa without any intervention. Group 2 received an injection of Cellbooster Lift immediately after the incision, whereas group 3 was treated with Elysee exosomes. Biopsy samples were collected at baseline, as well as on the 7th and 14th postoperative days, for histological analysis. Hematoxylin and eosin staining was used to assess epithelial regeneration, whereas Masson trichrome staining was utilized to evaluate collagen formation and granulation tissue organization.

Both the Cellbooster Lift and Elysee exosome-treated groups showed improvements in wound healing compared with the control group. Both treatments accelerated healing, evidenced by increased collagen deposition and well-organized granulation tissue. Although the clinical outcomes were comparable between the Cellbooster Lift and Elysee exosome groups, histological analysis revealed that exosomes led to advanced epithelial regeneration and collagen formation, indicating their enhanced efficacy in promoting wound recovery.

The injection of either Elysee exosomes or Cellbooster Lift enhanced the healing of oral mucosal wounds, with both treatments showing clinically similar improvements in recovery and tissue regeneration. However, histologically, exosomes demonstrated acceptable results, particularly in epithelial regeneration and collagen formation. These findings suggest that both therapies could be effective for oral wound healing, with exosomes offering an enhanced regenerative potential.