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Updated: Jan 6, 2026

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Cysteine-activated hydrogen selenide (H2Se) delivery from isoselenocyanates

Reis D Dorit1, Keyan Li1, Christopher A Steven1

  • 1Department of Chemistry and Biochemistry, Materials Science Institute, Knight Campus for Accelerating Scientific Impact, and Institute of Molecular Biology, University of Oregon, Eugene, Oregon, 97403-1253, USA. pluth@uoregon.edu.

Chemical Communications (Cambridge, England)
|October 30, 2025
PubMed
Summary

Aryl isoselenocyanates release hydrogen selenide (H2Se) when activated by cysteine. This discovery offers new tools for studying H2Se in biological systems and live cell imaging.

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