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Evaluating AI Chatbot Performance Against Prosthodontic Residents on the National Prosthodontic Resident Examination
The International Journal of Prosthodontics
|October 30, 2025
Summary
Artificial intelligence (AI) chatbots, like ChatGPT 3.5, show performance comparable to or exceeding prosthodontic residents on the National Prosthodontic Resident Examination. However, AI model variability necessitates careful evaluation before clinical integration.
Area of Science:
- Artificial Intelligence
- Dental Education
- Prosthodontics
Background:
- The integration of artificial intelligence (AI) into specialized fields like prosthodontics is rapidly advancing.
- Assessing AI performance against human experts is crucial for understanding its potential and limitations.
Purpose of the Study:
- To compare the performance of seven AI chatbots against U.S. prosthodontic residents on the National Prosthodontic Resident Examination (NPRE).
- To evaluate AI capabilities in a high-stakes academic setting within prosthodontics.
Main Methods:
- AI chatbots (ChatGPT 3.5, 4, 4o, Gemini, Claude 3, Copilot, Llama) responded to NPRE questions from 2011-2023.
- Responses were compared to official answer keys and resident performance.
- Statistical analysis included repeated measures ANOVA and Bonferroni post-hoc tests.
Main Results:
- Significant differences in performance were observed across AI models (p<0.001).
- ChatGPT 3.5 outperformed other AI models and matched resident performance.
- Copilot performed significantly worse than residents, while others showed comparable, yet variable, results.
Conclusions:
- AI chatbots, particularly ChatGPT 3.5, demonstrate proficiency on specialized prosthodontic exams.
- Variability in AI performance underscores the need for critical assessment before adoption in dental education.
- AI shows promise as a supplementary tool, but reliability concerns require further investigation.
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