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Updated: Jan 12, 2026

Conventional Repetitive Transcranial Magnetic Stimulation for Depression: A Step-by-Step Protocol
Published on: November 21, 2025
TMS is needed in Public Mental Health Services
Saxby Pridmore1, Paul B Fitzgerald2, Gregory M Peterson3
1Discipline of Psychiatry, University of Tasmania, Hobart, TAS, Australia.
Transcranial magnetic stimulation (TMS) offers a revolutionary treatment for major depressive disorder (MDD). This cost-effective therapy effectively treats medication non-responders, highlighting the need for increased public access.
Area of Science:
- Neuroscience
- Psychiatry
- Medical Technology
Background:
- Major depressive disorder (MDD) affects a significant portion of the population.
- Antidepressant medications are ineffective for roughly half of all MDD patients.
- Current treatment options for non-responders are limited.
Purpose of the Study:
- To evaluate the efficacy of Transcranial Magnetic Stimulation (TMS) for treating MDD.
- To assess the potential of TMS as a cost-effective intervention.
- To advocate for expanded availability of TMS within public mental health services.
Main Methods:
- Utilizing electromagnetic apparatus to modulate brain function in specific regions.
- Administering TMS to patients with major depressive disorder.
- Comparing TMS efficacy in medication responders versus non-responders.
Main Results:
- Transcranial magnetic stimulation (TMS) demonstrates significant efficacy in achieving remission for MDD patients who do not respond to antidepressant medication.
- TMS is characterized by minimal side effects.
- The intervention is identified as cost-effective.
Conclusions:
- TMS represents a revolutionary and essential treatment for major depressive disorder (MDD).
- Increased availability of TMS in public mental health services is warranted due to its effectiveness and cost-efficiency.
- TMS offers a viable therapeutic option for a substantial number of medication non-responders.
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11:11Protocol for Repetitive Transcranial Magnetic Stimulation with Symptom Provocation to Treat Obsessive-compulsive Disorder
Published on: November 25, 2025
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