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Updated: Jan 12, 2026

Avidity-based Extracellular Interaction Screening AVEXIS for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions
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Avidity-based Extracellular Interaction Screening AVEXIS for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions

Published on: March 5, 2012

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MetaLigand provides a prior-knowledge-guided framework for predicting non-peptide ligand mediated cell-cell

Ying Xin1, Yang Jin1, Cheng Qian1

  • 1Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Cell Reports Methods
|November 1, 2025
PubMed
Summary

MetaLigand infers non-peptide ligand (NPL) availability and interactions from transcriptomic data. This tool aids in understanding NPL-mediated cell communication in health and disease.

Keywords:
CP: computational biologyCP: systems biologycell-cell communicationligand-receptor interactionmetabolitenon-peptide ligandsingle-cell RNA sequencingspatial transcriptomics

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