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Patient Perspectives on Tic-Related Impairment: A Qualitative Examination
Emily Kuhn1, Brianna Wellen1, Matthew Richard Capriotti2
1Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis; and.
Neurology. Clinical Practice
|November 3, 2025
Summary
Patients with Tourette syndrome seek treatment for tic-related impairment, not just symptom reduction. This study identified six major themes of impairment, highlighting the need for patient-centered care.
Area of Science:
- Neurology
- Psychiatry
- Behavioral Science
Background:
- Traditional Tourette syndrome treatment focuses on reducing tic severity.
- Emerging research suggests patients seek treatment for broader reasons, including impairment.
- The relationship between tic severity and impairment is not fully understood.
Purpose of the Study:
- To qualitatively explore patient-reported tic-related impairment.
- To understand how tics interfere with daily life from the patient's perspective.
Main Methods:
- Data collected from 69 participants (aged 8-57) in two Comprehensive Behavioral Intervention for Tics trials.
- Responses to open-ended prompts about life interference were coded.
- An inductive, iterative coding approach was used by three tic disorder experts.
Main Results:
- Six major themes of tic-related impairment emerged: social interference, task interference, physical experiences, emotional distress, activity restriction, and sleep interference/fatigue.
- Fourteen minor themes were also identified.
- These findings underscore the multifaceted nature of tic-related impairment.
Conclusions:
- This study is a crucial first step in identifying and measuring patient-centered goals for Tourette syndrome treatment.
- Results emphasize the need to incorporate patient-reported outcomes into clinical practice and research.
- Addressing tic-related impairment is essential for improving quality of life in Tourette syndrome patients.
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