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Approach to Diagnosing and Managing Implantation Mycoses.

Dallas J Smith¹, Conceição Maria Pedrozo E Silva de Azevedo¹, Ahmed Fahal¹

¹Dr. Smith is from the Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia. Dr. Pedrozo e Silva de Azevedo is from the Department of Medicine, Federal University of Maranhão, São Luís, Brazil. Dr. Fahal is from the Mycetoma Research Center, University of Khartoum, Sudan. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York. Dr. Grijsen is from the Oxford University Clinical Research Unit Indonesia, Faculty of Medicine Universitas Indonesia, Jakarta, and the Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, United Kingdom. Dr. Hay is from King's College London, United Kingdom.

|November 3, 2025

Summary

Chromoblastomycosis, subcutaneous phaeohyphomycosis, and mycetoma are fungal skin infections causing significant illness. This article outlines diagnostic and management steps, emphasizing the skin

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Area of Science:

Mycology
Infectious Diseases
Dermatology

Background:

Chromoblastomycosis, subcutaneous phaeohyphomycosis, and mycetoma are significant implantation mycoses.
These infections lead to considerable morbidity and reduced quality of life.
Current data on global epidemiology and robust diagnostic/clinical options are limited.

Purpose of the Study:

To outline diagnostic and management strategies for these implantation mycoses.
To highlight the critical role of the skin in the diagnosis and management pathway.

Main Methods:

Review of diagnostic and clinical management steps for implantation mycoses.
Emphasis on dermatological presentation and initial assessment.

Main Results:

The skin serves as the primary site for initiating diagnosis and management.
A structured approach to diagnosis and management is presented.

Conclusions:

Effective diagnosis and management of these mycoses depend on recognizing skin manifestations.
Further research into epidemiology and improved clinical options is warranted.