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Updated: Aug 14, 2026

Modeling Charcot-Marie-Tooth Disease In Vitro by Transfecting Mouse Primary Motoneurons
Published on: January 7, 2019
[Serum cholinesterase as a model glycoprotein (author's transl)]
Abstract:
Human serum cholinesterase (EC 3.1.1.8) is a carbohydrate-rich glycoprotein, which reacts with 18 different lectins from plants and invertebrates by a specific precipitin reaction; most of the lectins combine with alkali-stable bound carbohydrate chains. One third of these lectin receptors appear after neuraminidase-treatment, two thirds can be demonstrated before and after removal of neuraminic acid. The specific lectin receptors of the alkali-labile carbohydrate chains are characterized and analyzed by chemical and serological methods.
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