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Updated: Jan 12, 2026

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
Published on: August 11, 2023
Anti-VEGF therapy - a new hope in AMD treatment
Ana-Maria Stoica1, Sanda Jurja1,2, Nejla Dervis3
1Department of Ophthalmology, "Sf. Apostol Andrei" County Emergency Clinical Hospital, Constanţa, Romania.
Abstract:
Choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) represents a significant global cause of visual impairment. Contemporary therapeutic approaches for neovascular AMD focus on inducing regression of CNV by inhibiting critical growth factors involved in angiogenesis. For nearly two decades, vascular endothelial growth factor (VEGF) has been the principal therapeutic target, with multiple intravitreally administered agents developed to achieve anatomical restoration and improved visual outcomes through sustained dosing.
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