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Updated: May 8, 2026

Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Durability of Pulsed Field Ablation Lesions: Current Understanding and Future Directions
Kars Neven1,2, Anna Füting1,2, Stefan Hartl1,2
1Department of Electrophysiology, Alfried Krupp Krankenhaus Essen, Germany.
None:
Pulsed field ablation (PFA) represents a paradigm shift in the catheter-based treatment of AF, offering myocardial-selective ablation through the non-thermal mechanism of irreversible electroporation. Despite promising early outcomes, the durability of PFA lesions, particularly over mid-and long-term follow-up, remains a critical area of investigation. This review incorporates preclinical and clinical data on PFA lesion durability, explores biophysical underpinnings, evaluates procedural variables influencing outcomes, and identifies ongoing challenges and future research priorities.
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