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Provider Perspectives on De-Implementation of Routine Blood Typing and Rh Immune Globulin Administration in the First
Emma V Gilmore1, Madeline V Smith1, Cecelia Tannous-Taylor1
1Department of Obstetrics and Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
Summary
Obstetrician-gynecologists want to stop routine Rh testing and Rh immune globulin for first trimester bleeding. Lack of evidence familiarity and support hinders this practice change, despite updated guidelines.
Area of Science:
- Obstetrics and Gynecology
- Reproductive Health
- Implementation Science
Background:
- Historically, Rh immune globulin prophylaxis was standard for Rh-negative individuals with first-trimester bleeding to prevent Rh sensitization.
- Evolving research has led professional societies to update recommendations, yet clinical practice has lagged behind.
- Understanding physician perspectives is crucial for de-implementing outdated practices.
Purpose of the Study:
- To identify barriers faced by obstetrician-gynecologists in de-implementing routine Rh testing and Rh immune globulin prophylaxis for first-trimester bleeding.
- To gather insights on strategies that could facilitate the discontinuation of this practice.
Main Methods:
- Qualitative in-depth interviews were conducted with 20 obstetrician-gynecologists across diverse practice settings in 11 states.
- The Integrated Behavior Model and Consolidated Framework for Implementation Research guided the interview process.
- Thematic analysis was employed to identify barriers and facilitators for de-implementation.
Main Results:
- Key barriers included limited provider familiarity with current evidence and insufficient time for practice change initiatives.
- Physicians expressed a desire to de-implement the routine practice but cited a lack of adequate support systems.
- Drivers for change included updated professional society guidance, further research on first-trimester Rh sensitization, leadership endorsement, and provider/patient education.
Conclusions:
- Obstetrician-gynecologists are receptive to de-implementing routine Rh testing and prophylaxis in early pregnancy bleeding.
- Successful de-implementation requires enhanced provider confidence in evidence, strong institutional leadership support, and aligned professional society recommendations.
- Addressing knowledge gaps and providing educational resources are essential for practice transformation.
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