Contemporary Management of Dermatofibrosarcoma Protuberans

Dermatofibrosarcoma protuberans is a rare, low-grade sarcoma characterized by lateral tentacle-like extensions into the surrounding subcutaneous tissue. Although surgical resection remains that mainstay of treatment, achieving negative margins is often challenging due to these irregular growth patterns and is similarly associated with high local recurrence. Different surgical approaches for dermatofibrosarcoma protuberans include wide local excision, Mohs micrographic surgery, and a multidisciplinary combined approach.