Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jan 11, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Local Control and Vertebral Compression Fractures After Stereotactic Body Radiotherapy for Spinal Metastases.

Ha Un Kim¹, Jinhong Jung¹, Young Seok Kim¹

¹Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.

Journal of Clinical Medicine

|November 13, 2025

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Role of anti-Müllerian hormone in predicting premature ovarian insufficiency after pelvic radiotherapy.

Gynecologic oncology reports·2026

Same author

Shielding assessment for multi-ion radiotherapy based on ion-specific dose-defined workloads.

Scientific reports·2026

Same author

Feasibility of omitting regional nodal irradiation in cT1-2N1 breast cancer with ypN1 disease after neoadjuvant chemotherapy (KROG 21-06).

Clinical and translational radiation oncology·2026

Same author

Oncologic outcomes and renal function preservation after stereotactic ablative body radiotherapy versus radiofrequency ablation in stage I renal cell carcinoma.

Clinical and translational radiation oncology·2026

Same author

Silencing of NUP62 overcomes osimertinib resistance via ubiquitination of survivin in non-small cell lung cancer cells.

British journal of cancer·2026

Same author

Adults with a history of melanoma have higher odds of laryngeal cancer in the United States.

JAAD international·2026

Same journal

Evidence-Based Clinical Recommendations for the Appropriate Use of Diagnostic Tests in Pediatric Allergology: Focus on Asthma, Rhinoconjunctivitis, and Keratoconjunctivitis Vernal.

Journal of clinical medicine·2026

Same journal

Surgical and Transcatheter Approach of a Failed Mitral Valve Repair: A Comprehensive Review on Selecting the Most Suitable Approach.

Journal of clinical medicine·2026

Same journal

Hybrid Metaheuristic Feature Selection for Breast Cancer Detection in Digital Mammography: A Feasibility Study with Nested Validation, Benchmarking, and External Stress Testing.

Journal of clinical medicine·2026

Same journal

Identity Transformation and the Role of Accountability in Recovery from Problematic Pornography Use: A Phenomenological-Hermeneutical Study.

Journal of clinical medicine·2026

Same journal

Does Early Surgical Treatment in Degenerative Cervical Myelopathy Have a Favorable Clinical Outcome and Impact on Quality of Life?

Journal of clinical medicine·2026

Same journal

Shear Wave Elastography in Musculoskeletal Imaging: A Narrative Review.

Journal of clinical medicine·2026

See all related articles

Stereotactic body radiotherapy (SBRT) effectively manages spinal metastases pain and controls tumors. While vertebral compression fractures (VCF) are a risk, SBRT offers a favorable balance of efficacy and toxicity for patients.

Area of Science:

Oncology
Radiation Oncology
Medical Physics

Background:

Spinal metastases significantly impact patient quality of life.
Effective treatment is crucial for pain relief and local tumor control.
Stereotactic body radiotherapy (SBRT) is an emerging option for spinal metastases.

Purpose of the Study:

To evaluate the efficacy and toxicity of SBRT for spinal metastases.
To assess pain control, local tumor control, and vertebral compression fracture (VCF) incidence.
To identify prognostic factors for local progression-free survival (LPFS) and VCF risk.

Main Methods:

Retrospective analysis of 179 patients with 217 spinal metastatic lesions treated with SBRT.
Dose fractionation varied (1-5 fractions) with specific Gy prescriptions.

Keywords:

metastasis spine stereotactic body radiotherapy vertebral compression fracture

More Related Videos

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Related Experiment Videos

Last Updated: Jan 11, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device

Published on: November 8, 2024

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

Patient-reported outcomes, local recurrence, LPFS, and painful VCF incidence were assessed.

Main Results:

An 80.8% overall pain response rate was observed.
1- and 2-year LPFS rates were 90.6% and 83.0%, respectively.
The 1- and 2-year cumulative incidence of painful VCF was 8.7% and 12.8%; a biologically effective dose (BED3) ≥104 Gy was a risk factor.

Conclusions:

SBRT shows high efficacy in pain and local tumor control for spinal metastases.
The risk of vertebral compression fractures (VCF) is acceptable with SBRT.
SBRT represents a valuable treatment modality for spinal metastases.