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Related Experiment Video

Updated: May 7, 2026

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
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Development of Compact Electronics for QEPAS Sensors.

Vincenzina Zecchino1,2, Luigi Lombardi3, Cristoforo Marzocca2

  • 1PolySense Lab, Inter-University Department of Physics, University and Polytechnic University of Bari, 70126 Bari, Italy.

Sensors (Basel, Switzerland)
|November 13, 2025
PubMed
Summary
This summary is machine-generated.

Compact electronics were developed for Quartz-Enhanced Photoacoustic Spectroscopy (QEPAS) gas sensors. This innovation enables portable, cost-effective QEPAS applications, overcoming previous size and cost limitations.

Keywords:
QEPASfront-end electronicsfunction generationlock-in amplifierquartz tuning fork

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Area of Science:

  • Gas sensing technologies
  • Spectroscopy
  • Acoustic sensing

Background:

  • Quartz-Enhanced Photoacoustic Spectroscopy (QEPAS) offers high sensitivity and selectivity for gas detection.
  • Current QEPAS systems are often limited by bulky and expensive electronic components, hindering portable applications like drone integration.

Purpose of the Study:

  • To develop compact and cost-effective electronic modules for QEPAS sensors.
  • To overcome the size and cost limitations of existing QEPAS instrumentation.

Main Methods:

  • Designed and realized a low-noise, fully differential preamplifier with digital output and programmable gain for the quartz tuning fork.
  • Integrated a compact FPGA board featuring a laser modulation signal generator and a CORDIC-algorithm-based lock-in amplifier.

Main Results:

  • Successfully developed and tested compact electronic modules for QEPAS.
  • Demonstrated the functionality of the developed electronics for detecting H2O and CO2 in ambient air using QEPAS sensors.

Conclusions:

  • The developed compact electronics enable portable and cost-effective QEPAS applications.
  • This advancement significantly broadens the potential applications of QEPAS technology, including on-board drone systems.