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Updated: Jan 11, 2026

Probing the Roles of Physical Forces in Early Chick Embryonic Morphogenesis
Published on: June 5, 2018
Searching for physical principles of morphogenesis
Nikolas Claussen1, Fridtjof Brauns2, Sebastian J Streichan1
1Department of Physics, University of California Santa Barbara, Santa Barbara, CA 93106, USA.
None:
In morphogenesis, biology uses physics to sculpt organs. Understanding this fascinating process requires interdisciplinary collaboration. We highlight recent work in the 'physics of development', with a focus on the interplay between quantitative experiments and mathematical theory. We argue that the role of theory in developmental biology lies in identifying and describing dynamical mechanisms - from the processing of positional information to mechanical pattern formation - independently of their molecular implementation. This level of abstraction provides a structured approach to embrace developmental complexity, but can propose experimental tests to verify its key tenets. We conclude with a sketch of future research perspectives in emerging synthetic morphogenesis systems, which may serve as a platform to distill principles of developmental self-organization.
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