Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Systemic Veins01:11

Overview of Systemic Veins

1.1K
Systemic veins are crucial blood vessels that return deoxygenated blood from various body tissues back to the heart. There are three systemic veins that return deoxygenated blood to the heart, they are as follows.
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...
1.1K
Veins of Thorax01:19

Veins of Thorax

1.9K
The azygos system is a crucial part of the body's circulatory system and drains most of the thorax. It comprises the azygos, hemiazygos, and accessory hemiazygos veins.
The azygos vein, positioned just right of the midline and anterior to the vertebral column, begins at the junction of the right ascending lumbar and subcostal veins, terminating in the superior vena cava. This vein drains blood from the right side of the thoracic wall, thoracic viscera, and posterior abdominal wall.
The...
1.9K
Veins of the Abdomen and Pelvis01:18

Veins of the Abdomen and Pelvis

1.5K
The human body is a complex system of interconnected parts, and the circulatory system plays a crucial role in maintaining overall health. One key component of this system is the inferior vena cava, a large vein responsible for returning blood from the abdominopelvic viscera and abdominal walls to the heart.
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
1.5K
Overview of Pulmonary Circulation01:19

Overview of Pulmonary Circulation

2.7K
The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
2.7K
Anastomoses01:19

Anastomoses

2.4K
In human anatomy, anastomosis refers to a connection or opening between two things, particularly between blood vessels or other tubular structures. The term is derived from the Greek term 'anastomosis,' which means 'outlet' or 'opening.' This natural network of connections plays a critical role in the survival and functionality of the human body.
Anastomoses can be formed at arterial, venous, and lymphatic vessels.
Arterial Anastomosis: These occur between arteries. They...
2.4K
Overview of Systemic and Pulmonary Circulation01:15

Overview of Systemic and Pulmonary Circulation

9.9K
The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
9.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Breathing Physiology into the Art of Neonatal Respiratory Care.

Clinics in perinatology·2026
Same journal

The Science and Art of Neonatal Respiratory Care.

Clinics in perinatology·2026
Same journal

Ex Utero Artificial Womb Support: Promising Future for Extremely Preterm Infants.

Clinics in perinatology·2026
Same journal

Advances in the Use of Cell-Based Therapies for Prevention of Bronchopulmonary Dysplasia.

Clinics in perinatology·2026
Same journal

Evaluation and Management of Genetic Respiratory Disorders Presenting as Hypoxemic Respiratory Failure in the Newborn Infant.

Clinics in perinatology·2026
Same journal

Modern Surfactant Delivery Methods with a Focus on Implementation of Surfactant Administration Through Laryngeal and Supraglottic Airways.

Clinics in perinatology·2026

Related Experiment Video

Updated: Jan 11, 2026

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

3.2K

Total Anomalous Pulmonary Venous Connections.

Sonia Voleti Chivukula1

  • 1Division of Pediatric Cardiology Department of Pediatrics Children's Heart Center, Mattel Children's Hospital University of California Los Angeles (UCLA) 200 Medical Plaza, Suite 330 Los Angeles, CA 90095, USA.

Clinics in Perinatology
|November 13, 2025
PubMed
Summary

Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart defect. Early diagnosis and surgical repair, especially sutureless techniques, significantly improve outcomes by reducing pulmonary venous obstruction.

Keywords:
Congenital heart diseaseEchocardiographyPrenatal diagnosisPulmonary venous obstructionTotal anomalous pulmonary venous connection

More Related Videos

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.1K
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.6K

Related Experiment Videos

Last Updated: Jan 11, 2026

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins
06:48

Three-Dimensional Echocardiographic Method for the Visualization and Assessment of Specific Parameters of the Pulmonary Veins

Published on: October 28, 2020

3.2K
Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.1K
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.6K

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Total anomalous pulmonary venous connection (TAPVC) is a rare congenital heart defect where pulmonary veins connect to the systemic venous circulation instead of the left atrium.
  • Survival in TAPVC necessitates an atrial communication, and prognosis is heavily influenced by the presence and severity of pulmonary venous obstruction.

Purpose of the Study:

  • To review the clinical presentation, diagnostic modalities, and management strategies for total anomalous pulmonary venous connection.
  • To highlight the prognostic significance of pulmonary venous obstruction and individual vein size.
  • To discuss the impact of modern surgical techniques on patient outcomes.

Main Methods:

  • Review of clinical presentations, diagnostic findings (prenatal and postnatal echocardiography), and treatment outcomes for TAPVC.
  • Emphasis on echocardiographic markers for diagnosis and outcome prediction.
  • Analysis of surgical repair strategies, including emergent and planned procedures, and the role of sutureless repair.

Main Results:

  • Clinical presentation of TAPVC ranges from severe neonatal cyanosis to milder symptoms in infancy.
  • Pulmonary venous obstruction is a critical determinant of prognosis; individual vein size is a predictive factor.
  • Postnatal echocardiography is the primary diagnostic tool.

Conclusions:

  • Surgical repair is the definitive treatment for TAPVC, with emergent surgery for obstruction and early planned repair for stable cases.
  • Modern surgical approaches, including sutureless repair, have decreased postoperative pulmonary venous obstruction and improved survival rates.
  • Accurate diagnosis and timely intervention are crucial for managing this complex congenital heart defect.