Related Experiment Video For Hypopharyngeal cancer
Updated: Jul 25, 2026

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
Published on: July 25, 2011
Imaging of Laryngeal and Hypopharyngeal Squamous Cell Cancers
Sugoto Mukherjee1, Anthony F Higinbotham1, Thomas J E Muttikal1
1Department of Radiology and Medical Imaging, University of Virginia Health System, 1215 Lee Street, Charlottesville, VA 22908, USA.
Abstract:
This article provides a comprehensive overview of imaging in the evaluation of laryngeal and hypopharyngeal squamous cell carcinomas. It highlights the critical role of computed tomography (CT), MR imaging, and PET/CT in staging, treatment planning, and surveillance. Key anatomic landmarks, patterns of tumor spread, imaging features relevant to TNM staging, and post-treatment changes are discussed. Emphasis is placed on identifying imaging findings that alter management, such as subsite evaluations, cartilage invasion, extralaryngeal extension, and regional nodal metastasis. The article also addresses common diagnostic challenges and pearls for accurate interpretation.

